==================================CMR01================================== 1. We have a most interesting patient who has Hodgkin's disease and has presented with a liver abscess due to Nocardia species! Request search for papers detailing infections, specifically liver abscesses, in patients with Hodgkin's disease; spectrum of clinical illness infections due to Nocardia sp.; infections on patients with Chronic Granulomatous disease. 1 UI - 86213390 AU - Jonsson S ; Wallace RJ Jr ; Hull SI ; Musher DM TI - Recurrent Nocardia pneumonia in an adult with chronic granulomatous disease. AB - The diagnosis of chronic granulomatous disease was made for the first time in a young adult when he presented with Nocardia asteroides pneumonia. Treatment with trimethoprim/sulfamethoxazole for 10 wk brought about an apparent cure of the infection. Two and one half years later N. asteroides pneumonia recurred and resulted in death from respiratory failure. Antibiotic susceptibility studies suggested that both episodes were caused by the same organism. This suggestion was supported by endonuclease restriction analysis, which showed that the plasmids from both Nocardia isolates were identical. Late recurrence of pneumonia caused by N. asteroides occurs only rarely. In this patient, recurrent infection appeared to be related to persistence of colonizing organisms in the host. MH - Adult ; Case Report ; Granulomatous Disease, Chronic/ COMPLICATIONS/*DIAGNOSIS ; Human ; Male ; Nocardia Infections/ COMPLICATIONS/*DIAGNOSIS ; Pneumonia/*DIAGNOSIS/ETIOLOGY ; Recurrence SO - Am Rev Respir Dis 1986 May;133(5):932-4 2 UI - 86208767 AU - Skibber JM ; Lotze MT ; Garra B ; Fauci A TI - Successful management of hepatic abscesses by percutaneous catheter drainage in chronic granulomatous disease. AB - Chronic granulomatous disease (CGD) is a disorder of polymorphonuclear leukocytes that can cause multiple recurrent hepatic abscesses in 40% of those patients with the disorder. The mortality rate from this complication of CGD is estimated at 27%. Treatment has consisted of extensive surgical debridement and drainage and prolonged antibiotic therapy; however, this approach is accompanied by high morbidity and the frequent need for reoperation. Successful percutaneous drainage of multiple hepatic abscesses in a patient who had previously undergone 10 operative procedures to manage hepatic abscesses is reported. With the development of imaging and percutaneous drainage techniques, as well as the recurrent nature of this problem, percutaneous management should be given consideration in appropriate patients with CGD with hepatic abscesses. MH - Adult ; Case Report ; Combined Modality Therapy ; Drainage/ *METHODS ; Female ; Granulomatous Disease, Chronic/*COMPLICATIONS ; Human ; Liver Abscess/ETIOLOGY/RADIOGRAPHY/*SURGERY ; Recurrence ; Reoperation ; Tomography, X-Ray Computed SO - Surgery 1986 May;99(5):626-30